In the mid to late '80s, a tool called remote data entry was available which replaced double key data entry and paper case report forms (CRFs) at the clinical trial study site. When remote data entry (RDE) was used, the drug sponsor would provide a portable computer to the investigational site. The coordinator would collect study-related patient data, and then enter the data directly into the computer via the specially designed user interface of data entry screens. The electronic data would then be monitored. After data cleanup, a floppy disk with the site's data would be sent to the sponsor via an overnight courier service. These tasks would occur periodically during the course of the clinical trial.