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University of Washington (UW)
designed to advance the use of molecular imaging in clinical investigations and trials.
Molecular imaging is an area of development in biotechnology, where specialized radiopharmaceuticals, or Positron Emission Tomography (PET) "imaging agents," are injected into the body to detect and trace abnormal cellular functions that are associated with health issues such as heart disease, neurological disorders and many forms of cancer. These imaging agents, which are visible using sophisticated imaging scanners, make it easier for physicians to non-invasively diagnose, monitor and potentially treat disease at the earliest stages of onset.
Through this collaboration, the UW's Department of Radiology will relocate a portion of its on-campus molecular tracer laboratories into Cardinal Health's PET manufacturing facility located in downtown Seattle. The UW laboratories that are part of the move will include one operated by Dr. John Grierson, who developed the PET agent F-18 fluorothymidine (FLT), which is now distributed nationally through Cardinal Health and is being used in several clinical trials. UW's Department of Radiology will have access to Cardinal Health's cyclotron, radiopharmaceutical products and research support services, to aid in the efficient operation of its research facility.
By co-locating in the same physical space, the two organizations will combine the University of Washington's internationally-recognized PET research and development expertise with Cardinal Health's expertise in the FDA-compliant production and distribution of PET imaging agents to accelerate the research, development and commercialization of new molecular imaging agents.
"Consistent with the cycle of innovation, we look forward to collaboratively working with Cardinal Health to develop new uses for molecular imaging tracers–and the clinical applications of tomorrow," said Dr. Norman J. Beauchamp, Jr., UW professor of radiology and chairman of UW's Department of Radiology.
Cardinal Health's Nuclear Pharmacy Services business operates the nation's largest network of radiopharmacies. The company has also strategically located its nationwide network of cyclotrons to enable many of its radiopharmacies to compound and dispense high-energy PET imaging agents in unit-dose form.
Cardinal Health has already begun the process of expanding its Seattle radiopharmacy facility to accommodate UW's new radiochemistry laboratory, where UW researchers will work alongside Cardinal Health staff and technicians. Renovations to the expanded facility are expected to be completed by the beginning of 2011.
"We are very proud to partner with the University of Washington to advance the future of molecular imaging with the development of this world-class facility," said John Rademacher, president of Cardinal Health's Nuclear and Pharmacy Services business. "This collaboration will provide us with exciting new opportunities to partner with innovators and pharmaceutical research organizations to enable the research, development and commercialization of new molecular imaging agents that have the potential to dramatically improve patient health."