Osteoarthritis: Two-Year Results Show Benefits of Orthokine Therapy
DÜSSELDORF, GERMANY, September 12, 2007-Within the scope of the German Osteoarthritis Trial (GOAT) the effects of different innovative medications in osteoarthritis (OA) therapy were studied. All 376 participants in the trial suffered from painful OA of the knee joint and were treated with Orthokine, hyaluronic acid, or placebo injections. Orthokine therapy uses autologous, anti-inflammatory proteins, which are isolated from the patient’s blood and injected into the joint. Six months after the treatment, the outcome differed depending on the therapy: The condition of Orthokine-treated patients was found to be much better than that of patients treated with hyaluronic acid or placebo. The trial was conducted by the Heinrich Heine University in collaboration with the Center for Molecular Orthopaedics (Düsseldorf, Germany) and was recently published in the scientific journal “Biodrugs.” In the meantime, results obtained over two years give further support to the therapy utilising autologous proteins.
In past years, scientists have set high hopes on so-called biologicals-therapies using biological substances. These should directly address the cause of the disease and as a result, be particularly effective. Following a long period of developing new approaches against OA-among others the Orthokine therapy-biologicals are in the clinical trial phase. During this phase, the GOAT study was a milestone in the clinical research of the use of biologicals in orthopaedics.
Behind the Buzz: Why Clinical Research Leaders Flock to SCOPE Summit
February 7th 2025In this episode, we meet with Micah Lieberman, Executive Conference Director for SCOPE Summit (Summit for Clinical Ops Executives) at Cambridge Innovation Institute. We will dive deep into the critical role of collaboration within the clinical research ecosystem. How do we bring together diverse stakeholders—sponsors, CROs, clinical trial tech innovators, suppliers, patients, sites, advocacy organizations, investors, and non-profits—to share best practices in trial design, program planning, innovation, and clinical operations? We’ll explore why it’s vital for thought leaders to step beyond their own organizations and learn from others, exchanging ideas that drive advancements in clinical research. Additionally, we’ll discuss the pivotal role of scientific conferences like SCOPE Summit in fostering these essential connections and collaborations, helping shape the future of clinical trials. Join us as we uncover how collective wisdom and cross-industry partnerships are transforming the landscape of clinical research.
Reaching Diverse Patient Populations With Personalized Treatment Methods
January 20th 2025Daejin Abidoye, head of solid tumors, oncology development, AbbVie, discusses a number of topics around diversity in clinical research including industry’s greatest challenges in reaching diverse patient populations, personalized treatment methods, recruitment strategies, and more.