Patient recruitment remains the largest impediment to clinical trials progress. Barriers to participation are numerous and as noted in this article, can be broken down into these buckets on the recruitment progression cycle—awareness, identification, information and consent, patient-centric operations, and accelerated regulatory approval. Each of these buckets or progressions contain a plethora of ideas, strategies, technologies, and choices. And at any one of these progressions, a potential participant can be lost.
The reality of patient recruitment is that its success depends on those myriad factors under the buckets, in addition to an individual’s behavior or personal beliefs. According to survey results in this white paper from IQVIA, “When asked what prevents them from participating in a trial, fears about their health and safety (62%) far outweighed concerns about time (37%), logistics (18%), and negative press about research (8%).” Further influences can be analyzed by gender, race, and ethnicity, all coalescing around choosing to participate.
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