Breathe Easier: Cancer R&D Innovation Puts Strong Focus on the Lung
IMS Health
Innovation in oncology continues to dominate the drug development pipeline, with accelerated approvals, increased funding and awareness, and an overall pipeline of almost 2,000 active products under study accounting for one-third of all pharmaceutical R&D. However, while many oncology indications are experiencing success in life extension with overall five-year survival rates at more than 66%, others such as lung cancer are struggling to achieve the same results, with a mere 16.8% of patients achieving five-year survival. While these rates may be low, innovation in lung cancer is at an all-time high; extending survival of lung cancer patients has become a large industry investment.
However, an interesting finding is that the U.S. has remained cost neutral over the last five years in R&D cost per-patient spend, in addition to remaining visit neutral in the area of lung cancer research (see chart). Ex-U.S. has experienced the opposite—with a correlation between increased patient visits and increased per-patient spend. What is fueling this increase in activity? Is this purely a result of globalization of research over the past five years? Or perhaps the U.S. has become more efficient in execution, thus controlling spend, but with little new outcomes. — IMS Health
FDA Approves Nipocalimab for the Treatment of Generalized Myasthenia Gravis
April 30th 2025Approval is based on results from the pivotal Vivacity-MG3 trial in which IMAAVY (nipocalimab-aahu) demonstrated superior disease control throughout 24 weeks when compared to placebo plus standard of care.
Improving Relationships and Diversifying the Site Selection Process
April 17th 2025In this episode of the Applied Clinical Trials Podcast, Liz Beatty, co-founder and chief strategy officer, Inato, discusses a number of topics around site engagement including community-based sites, the role of technology in improving site/sponsor relationships, how increased operational costs are impacting the industry, and more.
Behind the Buzz: Why Clinical Research Leaders Flock to SCOPE Summit
February 7th 2025In this episode, we meet with Micah Lieberman, Executive Conference Director for SCOPE Summit (Summit for Clinical Ops Executives) at Cambridge Innovation Institute. We will dive deep into the critical role of collaboration within the clinical research ecosystem. How do we bring together diverse stakeholders—sponsors, CROs, clinical trial tech innovators, suppliers, patients, sites, advocacy organizations, investors, and non-profits—to share best practices in trial design, program planning, innovation, and clinical operations? We’ll explore why it’s vital for thought leaders to step beyond their own organizations and learn from others, exchanging ideas that drive advancements in clinical research. Additionally, we’ll discuss the pivotal role of scientific conferences like SCOPE Summit in fostering these essential connections and collaborations, helping shape the future of clinical trials. Join us as we uncover how collective wisdom and cross-industry partnerships are transforming the landscape of clinical research.
