Advancing Clinical Research in GLP-1 Therapies: Insights From a Principal Investigator

Discover how GLP-1 therapies are redefining obesity and metabolic disorder research in this session led by Kimball A. Johnson, MD, of CenExel Decatur. Gain firsthand insights into the science, patient management strategies, and trial design approaches shaping the next generation of incretin-based studies.

Register Free: https://www.appliedclinicaltrialsonline.com/act_w/glp-1_therapies

Event overview:

GLP-1 receptor agonists have transformed the landscape of obesity and metabolic disorder management, offering unprecedented efficacy in weight reduction and metabolic health. As clinical development in this therapeutic area accelerates, understanding both the clinical impact and operational nuances of GLP-1 trials is critical for sponsors and CROs aiming to optimize study outcomes.

In this session, Kimball A. Johnson, MD, a leading principal investigator at CenExel Decatur, will provide a deep dive into the clinical and scientific underpinnings of GLP-1 therapies, drawing from her extensive experience conducting pivotal human trials. She will explore the broader health implications of these agents, share insights on managing adverse events, and discuss strategies for ensuring patient retention and high-quality data collection. Attendees will also gain perspective on comparing molecules such as semaglutide, tirzepatide, and emerging dual and triple agonists, as well as the evolving landscape of obesity and metabolic disorder research.

Key Learning Objectives:

• Understand the mechanisms of action, clinical efficacy, and safety profiles of current and emerging GLP-1 therapies.
• Gain practical insights into managing adverse events and optimizing patient adherence in clinical trials.
• Learn best practices for trial design, patient recruitment, and long-term follow-up in obesity and metabolic disorder studies.
• Explore the future of incretin-based therapies and their potential impact on patient health and clinical research priorities.
• Appreciate the perspective of a principal investigator on how sponsor and CRO collaboration can drive successful study outcomes.

Who Should Attend:

• Sponsors and study teams developing GLP-1 and obesity-related trials
• CRO representatives responsible for trial operations and site management
• Principal investigators and site staff engaged in metabolic disorder research
• Medical affairs and clinical strategy professionals seeking insights into trial design and patient outcomes

Speaker:

Kimball A. Johnson, MD
Chief Medical Director Task Force
Leader
CenExel Metabolic

Kimball A. Johnson, MD, is a board-certified diplomate of the American Board of Internal Medicine and previously an HIV specialist certified by the American Academy of HIV Medicine. She is also board-certified by the American Board of Integrative Holistic Medicine. A 1987 cum laude graduate of Emory University School of Medicine, Johnson holds a bachelor of science degree in physical education from Taylor University, where she studied exercise physiology and biomechanics. She began her medical career as a paramedic at Grady Memorial Hospital, gaining invaluable early experience in patient care.

Johnson is a diplomate of the American College of Physicians and the American Society of Internal Medicine , and an active participant in numerous professional organizations, including the American Medical Association, the Southern Medical Association, the Medical Association of Georgia, the American Medical Women’s Association, the AIDS Research Consortium of Atlanta (ARCA), the American College of Sports Medicine, and the American Academy of HIV Medicine.

A trailblazer in the HIV medical community, Johnson was involved at the onset of the US HIV epidemic in Atlanta. She participated in the original AZT and DDI clinical trials, marking the start of a prolific research career. She went on to serve as a sub investigator with the ARCA on multiple HIV trials and continued to advance the field through decades of dedicated clinical work.

In private practice for more than 30 years, Johnson specialized in internal medicine, integrative and holistic medicine, and HIV medicine. She is passionate about infectious disease research and has led or contributed to more than 300 clinical trials and helped randomize over 10,000 patients across phase I–IV studies.

Johnson is also a certified CrossFit Level 1 trainer and has served as a physician for the American College of Sports Medicine, the Ironman World Championship, and the Peachtree Road Race. She volunteered at the US Olympic Training Center in 1999 and now serves as medical director at CenExel Decatur, where she oversees care for underserved patients and leads multiple ongoing clinical trials, including COVID-19 research.

Register Free: https://www.appliedclinicaltrialsonline.com/act_w/glp-1_therapies