Commentary|Videos|July 29, 2025
Growing Excitement Around Biomarkers in Clinical Trials
Author(s)Andy Studna, Senior Editor
In this video interview, Michael Miller, chief operating officer at Quanterix, discusses how the use of biomarkers is expanding beyond exploratory endpoints to inform efficacy and patient selection, driving improved outcomes and greater efficiency in clinical research.
Advertisement
In a recent video interview with Applied Clinical Trials, Michael Miller, chief operating officer, Quanterix, discussed how the clinical research industry is increasingly integrating biomarkers. Biomarkers are particularly beneficial in neurology, where advancements in imaging and blood tests have improved trial outcomes, and in oncology, where multiomic approaches and protein tissue imaging aid in matching therapies to mutations. Synopsis professionals should focus on the biomarker's purpose, technical requirements, and regulatory compliance. Platform trials and biomarkers are also driving accelerated drug approvals. These advancements are crucial for biopharma companies navigating the shift between private and government-funded research.
ACT: Where does the clinical research industry currently stand with biomarker integration? Is it becoming more popular, is there hesitancy around it, excitement, etc.?
Miller: I think there is a lot of excitement about biomarkers in clinical trials right now, and a lot of that stems with some of the new uses. Currently, a lot of trials do include biomarkers. Today, many of them can be used for exploratory purposes or exploratory endpoints, but the real action, or the real excitement is around biomarkers starting to be used to understand the efficacy of the drug or to help understand selecting the right patients to be enrolled in a trial for a particular drug. Why is there excitement? Excitement is because that can make the clinical trial outcomes more successful and make the clinical trials more efficient, in terms of you're getting the right patients on the right drug, seeing better efficacy in those patients.
Newsletter
Stay current in clinical research with Applied Clinical Trials, providing expert insights, regulatory updates, and practical strategies for successful clinical trial design and execution.
Advertisement
Related Articles
- How Sponsors Can Modernize Tools to Support Physicians
September 9th 2025
Advertisement
Advertisement
Trending on Applied Clinical Trials Online
1
ACT Brief Episode 7: Veeva and Merck Trial Efficiency, DCT Barriers, and Glucose Monitoring Strategies
2
Pfizer, BioNTech’s Comirnaty Shows Strong Immune Response in Phase III Trial for COVID-19
3
AstraZeneca’s Tagrisso Shows Landmark Overall Survival Benefit in Non-Small Cell Lung Cancer
4
Summit Therapeutics’ Bispecific Antibody Shows Positive Survival Trend in Non-Small Cell Lung Cancer
5