This graph and table show the total number of studies registered on ClinicalTrials.gov since 2000, based on the First Received Date. The first version of ClinicalTrials.gov was made available to the public on February 29, 2000.

Indicates when the International Committee of Medical Journal Editors began requiring trial registration as a condition of publication (September 2005)


 Indicates when the expanded registration requirements of FDAAA began and were implemented on ClinicalTrials.gov (December 2007)