Oncodesign and UCB Enter into a Research Collaboration for the Early Development of New Therapeutic Agents in Neurodegenerative Diseases
The partnership is based on Oncodesign's Nanocyclix(R) technology platform for next generation kinase inhibitors and UCB?s expertise in neurology
Oncodesign
, a drug discovery company and oncology pharmacology service provider, announces today that it has entered into a research collaboration and exclusive license option with UCB, a global biopharmaceutical leader specialised in neurology and immunology. The collaboration will leverage the respective expertise of Oncodesign and UCB to bring innovative therapeutic solutions to patients suffering from neurodegenerative disorders. Oncodesign will apply its Nanocyclix technology on a kinase target selected by UCB with the aim of discovering potent and selective inhibitors that cross the blood brain barrier.
Oncodesign’s Nanocyclix technology is a proprietary medicinal chemistry platform based on small molecule macrocyclisation that gives access to potent and highly selective kinase inhibitors with attractive physicochemical and ADME properties. Oncodesign has identified Nanocyclix leads against a broad range of known and unexplored kinases with potential in different therapeutic areas and is engaged in multiple collaborations with pharmaceutical partners.
“This collaboration with UCB further establishes Oncodesign as a major player in the drug discovery field. It strengthens our strategy of early partnering with leading international pharmaceutical companies in fields outside of oncology. This, together with our internal focus on innovative programs against cancer, constitutes a strong basis for addressing major unmet needs in patients and value creation,” said Philippe Genne, Ph.D., chairman and chief executive officer of Oncodesign.
“We are very excited to partner with UCB for the first time on this exclusive research collaboration and license option in the field of neurodegenerative disorders, an area with high unmet needs for a large patient population. This new collaboration demonstrates the growing interest that the pharmaceutical industry has in our Nanocyclix technology. This allows us to discover innovative inhibitors for kinases that are otherwise difficult to address,” said Jan Hoflack, Ph.D., chief scientific officer and head of Oncodesign's discovery activities.
Phase III PROMINENT Trial Initiated to Evaluate Felzartamab for Primary Membranous Nephropathy
June 30th 2025The global Phase III PROMINENT trial has begun dosing patients to evaluate felzartamab in treating primary membranous nephropathy, a serious autoimmune kidney disorder with no FDA-approved therapies.
Unifying Industry to Better Understand GCP Guidance
May 7th 2025In this episode of the Applied Clinical Trials Podcast, David Nickerson, head of clinical quality management at EMD Serono; and Arlene Lee, director of product management, data quality & risk management solutions at Medidata, discuss the newest ICH E6(R3) GCP guidelines as well as how TransCelerate and ACRO have partnered to help stakeholders better acclimate to these guidelines.
Pfizer Reports Strong Phase III Results for Hympavzi in Hemophilia Patients with Inhibitors
June 26th 2025The Phase III BASIS trial found that once-weekly subcutaneous Hympavzi reduced treated bleed rates by 93% in patients with hemophilia A or B with inhibitors, offering a promising new prophylactic option for a population with limited therapeutic choices.
